COMPUTED TOMOGRAPHY IMAGE SEGMENTATION FOR ISCHEMIC STROKE LESION DELINEATION: A COMPREHENSIVE BIBLIOMETRIC ANALYSIS AND ADVANCED METHODOLOGICAL REVIEW
- Authors
-
-
Dr. Lily A. Simmons
Department of Psychology, Indiana University Bloomington, Bloomington, IN, USAAuthor -
Dr. Owen J. Martinez
School of Communication, University of North Texas, Denton, TX, USAAuthor
-
- Keywords:
- CT scan, Image segmentation, Ischemic stroke, Stroke image
- Abstract
-
Ischemic stroke remains a leading cause of global morbidity and mortality, necessitating rapid and accurate diagnosis for effective treatment. Computed Tomography (CT) imaging is a primary modality for initial assessment, particularly for distinguishing ischemic stroke from hemorrhagic stroke. Accurate, automated segmentation of ischemic stroke lesion areas from CT images is crucial for guiding clinical decisions, evaluating treatment efficacy, and predicting patient outcomes. This article presents a comprehensive bibliometric analysis of research trends from 2013 to 2023 and an in-depth survey of contemporary methodologies employed for CT scan image segmentation to identify ischemic stroke lesion areas. We meticulously explore the evolution of techniques from traditional image processing to advanced deep learning approaches, highlighting key trends, challenges, and future directions. The bibliometric analysis, encompassing over 2,000 publications, reveals a surging interest in the field, with significant contributions from China, the United States, and India. The methodological review emphasizes the dominance and superior performance of deep learning models, particularly Convolutional Neural Networks, while also addressing persistent challenges such as data scarcity, lesion subtlety, and model interpretability. The analysis underscores the critical need for robust, generalizable, and automated segmentation tools to improve diagnostic workflows and ultimately enhance patient care.
- Downloads
-
Download data is not yet available.
- References
-
[1] K. W. Muir, “Stroke,” Medicine, vol. 37, no. 2, pp. 109–114, Feb. 2009, doi: 10.1016/j.mpmed.2008.11.004.
[2] M. C. Leary and L. R. Caplan, “Acute, focal neurological symptoms,” Imaging Acute Neurologic Disease: A Symptom-Based Approach, pp. 187–208, 2014, doi: 10.1017/CBO9781139565653.013.
[3] V. L. Feigin et al., “Global, regional, and national burden of stroke and its risk factors, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019,” The Lancet Neurology, vol. 20, no. 10, pp. 795–820, 2021, doi: 10.1016/S1474-4422(21)00252-0.
[4] A. P. Okekunle et al., “Stroke in Africa: A systematic review and meta-analysis of the incidence and case-fatality rates,” International Journal of Stroke, vol. 18, no. 6, pp. 634–644, Jul. 2023, doi: 10.1177/17474930221147164.
[5] M. H. Rahbar et al., “Younger age of stroke in low‐middle income countries is related to healthcare access and quality,” Annals of Clinical and Translational Neurology, vol. 9, no. 3, pp. 415–427, Mar. 2022, doi: 10.1002/acn3.51507.
[6] R. O. Akinyemi et al., “Stroke in Africa: profile, progress, prospects and priorities,” Nature Reviews Neurology, vol. 17, no. 10, pp. 634–656, 2021, doi: 10.1038/s41582-021-00542-4.
[7] Z. Liu, C. Cao, S. Ding, Z. Liu, T. Han, and S. Liu, “Towards clinical diagnosis: Automated stroke lesion segmentation on multi-spectral MR image using convolutional neural network,” IEEE Access, vol. 6, pp. 5706–57016, 2018, doi: 10.1109/ACCESS.2018.2872939.
[8] P. Afshar, A. Mohammadi, and K. N. Plataniotis, “BayesCap: a Bayesian approach to brain tumor classification using capsule networks,” IEEE Signal Processing Letters, vol. 27, pp. 2024–2028, 2020, doi: 10.1109/LSP.2020.3034858.
[9] U. A. Bukar, M. S. Sayeed, S. F. A. Razak, S. Yogarayan, O. A. Amodu, and R. A. R. Mahmood, “A method for analyzing text using VOSviewer,” MethodsX, vol. 11, Dec. 2023, doi: 10.1016/j.mex.2023.102339.
[10] G. M. N. R. Gajanayake, R. D. Yapa, and B. Hewawithana, “Comparison of standard image segmentation methods for segmentation of brain tumors from 2D MR images,” in 2009 International Conference on Industrial and Information Systems (ICIIS), Dec. 2009, pp. 301–305, doi: 10.1109/ICIINFS.2009.5429848.
[11] X. Zhang et al., “CarveMix: a simple data augmentation method for brain lesion segmentation,” in Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics), vol. 12901 LNCS, 2021, pp. 196–205, doi: 10.1007/978-3-030-87193-2_19.
[12] Y. Yu et al., “Intracranial calcification is predictive for hemorrhagic transformation and prognosis after intravenous thrombolysis in non-cardioembolic stroke patients,” Journal of Atherosclerosis and Thrombosis, vol. 28, no. 4, pp. 356–364, Apr. 2021, doi: 10.5551/jat.55889.
[13] T. Zhou, “Deep learning for semantic segmentation in multimodal medical images: application on brain tumor segmentation from multimodal magnetic resonance imaging,” Ph.D. thesis, Department of Computer Science, Normandie Université, 2022.
[14] A. Svecic, D. Roberge, and S. Kadoury, “Prediction of inter-fractional radiotherapy dose plans with domain translation in spatiotemporal embeddings,” Medical Image Analysis, vol. 64, Aug. 2020, doi: 10.1016/j.media.2020.101728.
[15] M. Khoshkhabar, S. Meshgini, R. Afrouzian, and S. Danishvar, “Automatic liver tumor segmentation from CT images using graph convolutional network,” Sensors, vol. 23, no. 17, Sep. 2023, doi: 10.3390/s23177561.
[16] F. Özcan, O. Uçan, S. Karaçam, and D. Tunçman, “Fully automatic liver and tumor segmentation from CT image using an AIM-Unet,” Bioengineering, vol. 10, no. 2, Feb. 2023, doi: 10.3390/bioengineering10020215.
[17] R. V. Manjunath and K. Kwadiki, “Automatic liver and tumour segmentation from CT images using deep learning algorithm,” Results in Control and Optimization, vol. 6, Mar. 2022, doi: 10.1016/j.rico.2021.100087.
[18] G. Chlebus, A. Schenk, J. H. Moltz, B. van Ginneken, H. K. Hahn, and H. Meine, “Automatic liver tumor segmentation in CT with fully convolutional neural networks and object-based postprocessing,” Scientific reports, vol. 8, no. 1, Jul. 2018.
[19] M. Zhang, Z. Kong, W. Zhu, F. Yan, and C. Xie, “Pulmonary nodule detection based on 3D feature pyramid network with incorporated squeeze-and-excitation-attention mechanism,” Concurrency and Computation: Practice and Experience, vol. 35, no. 16, 2023.
[20] T.-Y. Lin, P. Dollar, R. Girshick, K. He, B. Hariharan, and S. Belongie, “Feature pyramid networks for object detection,” in 2017 IEEE Conference on Computer Vision and Pattern Recognition (CVPR), Jul. 2017, pp. 936–944, doi: 10.1109/CVPR.2017.106.
[21] M. Prastawa, E. Bullitt, S. Ho, and G. Gerig, “A brain tumor segmentation framework based on outlier detection,” Medical Image Analysis, vol. 8, no. 3, pp. 275–283, Sep. 2004, doi: 10.1016/j.media.2004.06.007.
[22] P. Schmidt et al., “An automated tool for detection of FLAIR-hyperintense white-matter lesions in multiple sclerosis,” NeuroImage, vol. 59, no. 4, pp. 3774–3783, Feb. 2012, doi: 10.1016/j.neuroimage.2011.11.032.
[23] S. Doyle, F. Vasseur, M. Dojat, and F. Forbes, “Fully automatic brain tumor segmentation from multiple MR sequences using hidden Markov fields and variational EM,” MICCAI Challenge on Multimodal Brain Tumor Segmentation, pp. 18–22, 2013.
[24] A. Gooya, K. M. Pohl, M. Bilello, G. Biros, and C. Davatzikos, “Joint segmentation and deformable registration of brain scans guided by a tumor growth model,” in Medical Image Computing and Computer-Assisted Intervention--MICCAI 2011: 14th International Conference, Toronto, Canada, 2011, pp. 532–540, doi: 10.1007/978-3-642-23629-7_65.
[25] S. Parisot, H. Duffau, S. Chemouny, and N. Paragios, “Joint tumor segmentation and dense deformable registration of brain MR images,” in International conference on medical image computing and computer-assisted intervention, 2012, pp. 651–658, doi: 10.1007/978-3-642-33418-4_80.
[26] X. Liu, M. Niethammer, R. Kwitt, M. McCormick, and S. Aylward, “Low-rank to the rescue-atlas-based analyses in the presence of pathologies,” in Medical Image Computing and Computer-Assisted Intervention--MICCAI 2014: 17th International Conference, Boston, 2014, pp. 97–104, doi: 10.1007/978-3-319-10443-0_13.
[27] Y. LeCun, L. Bottou, Y. Bengio, and P. Haffner, “Gradient-based learning applied to document recognition,” Proceedings of the IEEE, vol. 86, no. 11, pp. 2278--2324, 2002, doi: 10.1109/9780470544976.ch9.
[28] A. Krizhevsky, I. Sutskever, and G. E. Hinton, “ImageNet classification with deep convolutional neural networks,” Communications of the ACM, vol. 60, no. 6, pp. 84–90, 2017, doi: 10.1145/3065386.
[29] D. C. Cireşan, A. Giusti, L. M. Gambardella, and J. Schmidhuber, “Deep neural networks segment neuronal membranes in electron microscopy images,” Advances in Neural Information Processing Systems, vol. 4, pp. 2843–2851, 2012.
[30] D. Zikic, Y. Ioannou, M. Brown, and A. Criminisi, “Segmentation of brain tumor tissues with convolutional neural networks,” Proceedings MICCAI-BRATS, vol. 36, pp. 36–39, 2014.
[31] M. Havaei et al., “Brain tumor segmentation with deep neural networks,” Medical image analysis, vol. 35, pp. 18–31, 2017.
[32] S. Pereira, A. Pinto, V. Alves, and C. A. Silva, “Deep convolutional neural networks for the segmentation of gliomas in multisequence MRI,” International Workshop on Brainlesion: Glioma, Multiple Sclerosis, Stroke and Traumatic Brain Injuries, pp. 131–143, 2016, doi: 10.1007/978-3-319-30858-6_12.
[33] O. Maier et al., “ISLES 2015-a public evaluation benchmark for ischemic stroke lesion segmentation from multispectral MRI,” Medical Image Analysis, vol. 35, pp. 250–269, Jan. 2017, doi: 10.1016/j.media.2016.07.009.
[34] L. Giancardo, A. Niktabe, L. Ocasio, R. Abdelkhaleq, S. Salazar-Marioni, and S. A. Sheth, “Segmentation of acute stroke infarct core using image-level labels on CT-angiography,” NeuroImage: Clinical, vol. 37, 2023, doi: 10.1016/j.nicl.2023.103362.
[35] B. Felfeliyan et al., “Self-supervised-RCNN for medical image segmentation with limited data annotation,” Computerized Medical Imaging and Graphics, vol. 109, Oct. 2023, doi: 10.1016/j.compmedimag.2023.102297.
[36] M. Camacho et al., “Explainable classification of Parkinson’s disease using deep learning trained on a large multi-center database of T-weighted MRI datasets,” NeuroImage: Clinical, vol. 38, Oct. 2023, doi: 10.1016/j.nicl.2023.103405.
[37] X. Zeng et al., “Reciprocal learning for semi-supervised segmentation,” in Medical Image Computing and Computer Assisted Intervention--MICCAI 2021: 24th International Conference, Strasbourg, France, 2021, pp. 352–361, doi: 10.1007/978-3-030-87196-3_33.
[38] J. Wang and T. Lukasiewicz, “Rethinking bayesian deep learning methods for semi-supervised volumetric medical image segmentation,” in Proceedings of the IEEE Computer Society Conference on Computer Vision and Pattern Recognition, 2022, pp. 182–190, doi: 10.1109/CVPR52688.2022.00028.
[39] S. Gao, H. Zhou, Y. Gao, and X. Zhuang, “BayeSeg: Bayesian modeling for medical image segmentation with interpretable generalizability,” Medical Image Analysis, vol. 89, 2023, doi: 10.1016/j.media.2023.102889.
- Downloads
- Published
- 2024-12-07
- Section
- Articles
- License
-
All articles published by The Parthenon Frontiers and its associated journals are distributed under the terms of the Creative Commons Attribution (CC BY 4.0) International License unless otherwise stated.
Authors retain full copyright of their published work. By submitting their manuscript, authors agree to grant The Parthenon Frontiers a non-exclusive license to publish, archive, and distribute the article worldwide. Authors are free to:
-
Share their article on personal websites, institutional repositories, or social media platforms.
-
Reuse their content in future works, presentations, or educational materials, provided proper citation of the original publication.
-
How to Cite
Similar Articles
- Dr. Caroline M. Walsh, Dr. Joshua L. Bennett, ENHANCED DIABETES PREDICTION VIA STACKED ENSEMBLE MACHINE LEARNING , European Journal of Emerging Cloud and Quantum Computing: Vol. 1 No. 01 (2024): Volume 01 Issue 01
- Dr. Celso Zito, Dr. Osirian Dawn, ENHANCED SUPPORT VECTOR REGRESSION PERFORMANCE THROUGH HARRIS HAWKS OPTIMIZATION FOR PARAMETER SELECTION , European Journal of Emerging Cloud and Quantum Computing: Vol. 1 No. 01 (2024): Volume 01 Issue 01
- Dr. Caedin R. Velmorin, Dr. Mireya T. Solvenic, A FRAMEWORK FOR INTEGRATING QUANTUM COMPUTING WITH MULTI-CLOUD ARCHITECTURES: ENHANCING COMPUTATIONAL EFFICIENCY AND SECURITY , European Journal of Emerging Cloud and Quantum Computing: Vol. 1 No. 01 (2024): Volume 01 Issue 01
You may also start an advanced similarity search for this article.